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Pharmaceutical filling machine solutions provider-Pharmaceutical Liquid Filling Equipment

We are consistently committed to supporting clients to design and build clean workshops, pharmaceutical turnkey project with worriless solutions.

Clean room turnkey project solution provider-cleanroom manufacturer&supplier

Cleanroom project means blocking out and excluding all the pollutants such as microparticles, harmful air, bacteria, etc, within a certain space, reasonably distribute the overall plant structure in the area to meet the requirements of the production process; and controls the temperature, humidity, cleanliness, space height, room pressure, airflow velocity, airflow distribution, noise, vibration, electric distribution, lighting, static electricity, etc, in the effective space(cleanroom) within a certain area of requirements. It' s a specially designed room.

pharmaceutical filling machine solution provider - cleanroom for filling line

We are consistently committed to supporting clients to design and build clean workshops, pharmaceutical turnkey project with worriless solutions.

Pharmaceutical Engineering project solution provider & manufacturer

We are consistently committed to supporting clients to design and build clean workshops, pharmaceutical turnkey project with worriless solutions.

Pharmaceutical industry turnkey project solution provider -production workshop

We are consistently committed to supporting clients to design and build clean workshops, pharmaceutical turnkey project with worriless solutions.

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3+
Production Base

20+
Years’ rich Experience

51+
Projects in 51 Countries

300+
Loyal Clientele

Shanghai Marya is a pharmaceutical engineering turnkey solution provider specializing in Pharmaceutical machinery, engineering design, cleanroom project，project management and validation. We have three factories and a number of experts and technicians who have been engaged in pharmaceutical and medical industries for more than 20 years. Worriless and relieved solution for customer is our value proposition, we are consistently committed to helping clients to design and build clean workshops, pharmaceutical engineering solutions.

What We Can Do

Shanghai Marya own the ability to provide a perfect solution in the whole pharmaceutical or cleanroom project.

Cleanroom Solution

The one stop solution for cleanroom means blocking out and excluding all the pollutants such as microparticles,harmful air,bacteria,etc,within a certain space,reasonably distribute the overall plant structure in the area to meet the requirements of the production process;and controls the temperature,humidity,cleanliness,space height,room pressure,airflow velocity,airflow distribution,noise,vibration,electric distribution,lighting,static electricity,etc,in the effective space(cleanroom) within a certain area of requirements, and it’s a specially designed room; no matter how the external air condition changes, the cleanliness,temperature and humidity,pressure and other performance characteristics of the cleanroom can all maintain and ensure the original design requirements and environmental protection requirements;

Injection Solution

The application plan of the overall solution for aseptic small volume preparations specifically includes a series of fully automated production equipment and information management system for the production of sterile drugs such as vials of powder injection/fluid injection, ampoules, cartridges, pre-filling needle, BFS,etc, and it realized the deep integration of information technology and manufacturing technology, so as to creat a digital and intelligent manufacturing factory; this kind of equipment focus on the fields of high value-added biological drugs and anti-tumor drugs, etc, It has high flexibility and can meet the flexible production demands of batch drug production of pharmaceutical companies or the alternate production of multiple kinds of drugs.

IV Fluid Solution

Known as Large Volume Parenteral (LVP), which usually refers to liquid sterilization preparations with a volume greater than or equal to 50ml and directly injected into the body by intravenous drip, the packaging forms include glass bottle, plastic bottle, non-PVC soft bag and vertical soft bag and other packaging forms; large infusion, tablets, liquid injections, powder injections and capsules are collectively referred to five important preparations in the global pharmaceutical industry. According to its clinical use, large infusions can be divided into fluid balance infusions, antibiotics infusions, nutritional infusions and other therapeutic infusions. They are mainly used to supplement body fluid, electrolytes and nutrition, and can be used as plasma substitutes to maintain blood pressure;

Oral Liquid Solution

Oral liquid/syrup is a kind of oral liquid preparation based on traditional Chinese medicine decoction, extracted from the effective ingredients of the medicine, added with additives such as flavoring agent, bacteriostantic agent, etc. Through preparation, filling and sealing, sterilization, packaging and other processes, The overall solution for the oral liquid/syrup is composed of extraction workshop, preparation workshop, packaging workshop,intelligent warehouse and other functional modules. It builds a big data integration platform for traditional Chinese medicine production which completely integrated the information of process equipment, cleanroom engineering and equipment, control system and software system into a digital pharmaceutical factory model, and realized the effective integration of all kinds of data from process equipment, production lines, workshops of the whole factory, and meet the requirements of high efficiency, high quality, safety and environmental protection in the production and operation of traditional Chinese medicine;

Solid Medicine Solution

Compared with the liquid preparations, solid preparations have the common characteristics of better physical and chemical stability, lower manufacturing cost, and convenience in taking and carrying. No matter what production process, the granulation procedures at the first stage of tablet, capsule and granule production are similar, such as mixing, granulation, drying and sorting etc. The main equipments are: granulator, grinding and granulate machine, general mixer, tablet machine / capsule filling machine, coating machine, etc.

Water Treatment & Preparation Solution

Liquid technics overall solution mainly includes liquid technic system equipment/system, liquid utilities/systems, liquid piping system and cleaning and sterilization module equipment / system. We can provide customers with cell culture and extraction, medium preparation, cleaning and sterilization, and aseptic preparation and other process systems, and purified water, injection water, pure steam and other clean utility system from many fields such as monoclonal antibody, vaccine, insulin, LVP, blood products, biological products, oral solid preparation, traditional Chinese medicine, implantable medical device, etc. Professionally provide customers with overall solutions for clean fluid processes. Liquid technics overall solution also include clean utility equipment, such as purified water machine, injection water machine, pure clean machine generator, liquid module, CIP/SIP module, biological wastewater inactivation module, temperature control module and other equipment or systems.

View All Solutions

Why Choose Us

About Marya

Engineering design team with more than 20 years of experience

Our experienced engineering team has more than 20 years experience in cleanroom design and construction. We can ensure that the process and materials for your plant are designed and manufactured in the most cost-effective manner with reliable quality, and fulfil GMP/FDA/ISO/SGS requirement.

Maryas' 3 manufacturing plants for cleanroom projects and pharmaceutical equipments are all under strict quality management systems certified to ISO9001 with a focus on continuous quality improvement.

Experienced, professional, high-efficiency and strictly stick to the schedule, our installation engineers and workers team have successfully installed more than 300 projects in 51 countries with high customer satisfaction.

The R&D and design personnel are composed of experienced senior engineers and technicians. Using advanced production and testing equipment with high accuracy.

Adhere to the philosophy of "customer-centric", Marya creates the ultimate service experience with the heart of the craftsman! We are always on the way to create more value for customers.

What We Have Done

case

Malaysia Prefilled Syringe Filling Production Line Project

Argentina Ampoule and Vial Production Line Project

A pharmaceutical company needs a high-quality ampoule filling production line and vial powder filling production line.

What Our Clients Says

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Malaysia Client

Marya's marketing team is the best I've ever seen China in communication and service, they make everything clear and keep me updated in production and shipping progress, I will definitely keep cooperating with them.

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Dominica Client

Marya installation team is very commited to their work, very helpful and help us build our own installation team.

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Bangladesh Client

Marya is trustworthy, with excellent engineering quality, experienced technical team and excellent customer service.

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Malaysia Client

What We Manufacture

Shanghai marya is an overall solution provider specializing in pharmaceutical machinery, engineering design, cleanroom project, project management and validation.

Ampoule Liquid Filling Sealing Production Line

The automatic Ampoule Liquid Filling Sealing Production Line is composed of ultrasonic bottle washing machine, dryer sterilizer and ampoule filling and sealing machine. It can complete spraying water, ultrasonic cleaning, air & water flushing of inner and outer wall of ampoule bottle, preheating, drying and sterilization, heat source removing, cooling, (nitrogen pre-filling), filling, (nitrogen post-filling), ampoule sealing and other complex functions, realizing automatic production of the whole process. Each machine can be used separately or in linkage line. The whole line is mainly used for ampoule injections filling in pharmaceutical factories and the general type can also be used for antibiotic vial injection filling or powder filling.

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Vial Liquid Filling Sealing Production Line

Marya is one of the best Liquid Vial Filling Machine manufacturers, can provide a wide range of automatic vial filling production line machines for the pharmaceutical industry. Such as vial filling and capping machine 、vial stoppering machine. Capable of handling vial sizes up to 100 ml and speeds up to 36000 per hour. Our vial filling machine can meet any requirement you need.

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Vial Powder Production Line

Our expertly designed dry powder injection filling machines maximize filling accuracy, prevent product contamination and reduce environmental risks. The custom-designed Open-RABS isolation protection system and the 100 laminar flow system provide further protection for aseptic powder filling.

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Aseptic pre-filled syringe filling and sealing line

As a professional prefilled syringe filling machine manufacturers, we produce high production capacity pfs filling machines for batch filling operations. Fully automatic design, clean laminar flow protection in the whole production process, servo system control, can complete your various needs of syringe filling applications.

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Plastic Bottle BFS Machine

Blow fill seal equipment entire production control process is completed by the computer program according to the predetermined program. The possible risks (environment, temperature, pressure difference, etc.) in the process are monitored by the computer control system according to the set parameters. This is the filling process with the strongest sterility guarantee capability at present. Marya as an excelent pharmaceutical BFS machine manufacturer, can provide customized machine for liquid filling in pharmaceutical, chemical and food industries with aseptic or non-aseptic packaging in plastic containers.

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Syrup filling production line

Marya's pharmaceutical filling machines are suitable for a range of products from liquid to powder and even granular applications. Our dry syrup filling machine has simple adjustment of operation data, high filling accuracy and convenient use. Can be customized according to the actual needs of customers.

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Oral liquid production line

Marya oral liquid pharmaceutical filling machine is suitable for the production of packaging lines for oral liquid bottles and other small-dose solutions in the pharmaceutical, health care, food and other industries.

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Cartridge Filling Line

The cartridge filling line is composed of an ultrasonic bottle washing machine, an air-drying silicone oil injection integrated machine, a sterilization dryer, and a cartridge stoppering filling capping machine. It can complete complex functions such as spraying water, ultrasonic cleaning, air & water flushing of the inner and outer walls of cartridge bottles, air drying, silicone oil spraying, preheating, drying, and sterilization, heat source removing, cooling, stoppering, filling, capping, etc., realizing automatic production of the whole process.

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Cleanroom Project

Cleanroom project means blocking and eliminating all pollutants such as microparticles, harmful air and bacteria in a certain space, and reasonably distributing the overall plant structure in the area to meet the requirements of the production process, and controlling the temperature, humidity, cleanliness, space height, room pressure, airflow velocity, air distribution, noise, vibration, electric distribution, lighting, static electricity, etc. in the space (clean room) within a certain area requirement. This is a specially designed room.

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Cleanroom Air Handling Unit (AHU)

The cleanroom AHU realizes the functions of refrigeration, heating, dehumidifying, heating, humidification, purification and sterilization through a variety of heat and humidity treatment schemes and air purification treatment, so as to achieve precise control of the indoor environment temperature, humidity, and cleanliness.

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HVAC Air Duct System

HVAC Air Duct System is the core of cleanroom operation; the design and installation of air ducts directly affect the quality of cleanroom engineering; reasonable design and installation of cleanroom air ducts can also save energy consumption and reduce pipe elbows for cleanroom operation, reducing unnecessary length of pipelines and reasonably designing the size of the pipelines, and can reasonably reduce the operating power loss of the combined air-conditioning unit and other issues.

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Cleanroom Air Showers

Cleanroom Air shower room is a kind of local purification equipment with strong versatility, which is installed between clean room and unclean room. When people and goods want to enter the clean area, they need to be blown through the wind shower room. The clean air can remove the dust carried by people and goods, and can effectively block or reduce the dust source into the clean area.

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Shanghai marya is an overall solution provider specializing in pharmaceutical machinery, engineering design, cleanroom project, project management and validation.

Ampoule Liquid Filling Sealing Production Line

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Who Support Us

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What’s New

2023-09

Malaysian Client’s Visit to Marya’s Pharmaceutical Machinery Factory

In June 2023, a Malaysian client came to Marya’s pharmaceutical machinery factory for inspection. The purpose of this visit was to conduct the pre-FAT inspection on the quality, function and performance of their purchased syringe filling machine with isolator and plunger rod screwing labeling machine from us. Marya’s General Manager and director accompanied the client and communicated with him throughout the visit.

2023-09

Egyptian Client’s Visit to Marya’s Cleanroom Factory

In June 2023, Egyptian client came to visit and inspected Marya’s cleanroom factory. The main purpose of this visit is to inspect the ordered cleanroom materials, equipment and water chiller. And Marya's cleanroom technical director accompanied the chairman and communicated with him about the cleanroom project process.

2023-09

Marya Cleanroom Cargoes Sent to Uganda

Marya-Uganda cleanroom turnkey project was comfirmed in July and cargoes are now officially shipped in September. The cleanroom materials and equipment ordered by the client will be shipped on time and will soon be transported to the production line of the project for use.

2023-09

Shanghai Marya Participated in Pharmaconex Exhibition 2023

On September 5, 2023, the 10th Pharmaconex ended successfully at the Cairo International Convention Center. Shanghai Marya was invited to participate in this exhibition, showcasing a series of cutting-edge pharmaceutical equipment and solutions tailored for the pharmaceutical industry, including small capacity sterile preparation equipment (ampoule filling line, vial filling line, prefilled syringe filling line), large capacity sterile injection equipment (BFS machine, glass bottle/soft bag/plastic bottle IV infusion filling line), packaging machinery, and cleanroom turnkey engineering.

Because of persistence, so we are excellent

Work with the industry's technical experts, climb the peak and create the future intelligently.

CONTACT

Shanghai Office: NO211, North Fute Road, Pudong area, Shanghai, China, 200131

Changsha Office: Room 23069, Block 6, Forte Star Shine World, Yuhua District, Changsha, Hunan province

Factory 1: Hunan Marya Technology Co., Ltd. Address: No. 7 Plant, SANY Industrial Park, No. 1, SANY Road, Changsha Pilot Free Trade Zone, Hunan Province, China, 410100

Factory 2: No 555, Yupan Road, Weitang Town, Xiangcheng District, Suzhou, Jiangsu Province, China

Factory 3: 15-A, Venture Capital Industrial Square, Yanghe Road, Suzhou Industrial Park

Tel:+86-13507449007

E-Mail：info@marya.com.cn