PRODUCT CATEGORIES:
Vial Liquid Filling Sealing Production Line
1. Introduction
The vial liquid filling line is composed of ultrasonic vial washing machine, dryer sterilizer, vial injectable filling machine, vial stoppering machine and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, depyrogenation, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.
Vial Bottle/Stopper/Cap Picture |
Image after filling and sealing |
2. Performance Features
► The whole aseptic vial liquid filling sealing production line meets new GMP requirements, and the cleaning effect meets the new Pharmacopoeia standards and requirements;
► The whole injectable vial filling line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level;
► Applicable specification: 1ml-100ml vial (as per user’s requirement);
► Production Capacity of pharmaceutical vial filling machine: 1000-36000BPH;
► Number of filling head: 1-20, to be selected according to the output;
► Filling Accuracy: ≤±1% (according to drug characteristics);
► The vial liquid filling machine adopts various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;
► Capping qualified rate: ≥99.9%;
► Compact and simple structure, occupies less area;
► Stable product performance, easy and reliable operation, beautiful appearance;
► High degree of automation, few operators required;
► Single row or double row filling;
► Optional real-time display and printing system of sterilization temperature;
► The heat in the hot air circulation tunnel oven is evenly distributed, and the depyrogenation effect is good;
► Optional online sterilization function for the cooling section of hot air circulation tunnel oven;
► Optional open-RABS isolation protection system and class 100 laminar flow hood protection;
► Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;
► The capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution;
► This pharma filling machine can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.;
► Full-line linkage control function;
► To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used;
► Applicable for wide range of bottle specifications, and easy to replace mould;
► The products can be customized according to customer’s actual demand.
3. Parameter Specification
Model |
KGF4 |
KGF6 |
KGF8 |
KGF10 |
KGF12 |
KGF20 |
KGF24 |
Applicable specifications |
2~30ml vialbottles |
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Filling heads |
4 |
6 |
8 |
10 |
12 |
20 |
24 |
Production capacity |
50-100bts/min |
80-150bts/min |
100-200bts/min |
150-300bts/min |
200-400bts/min |
250-500bts/min |
300-600bts/min |
Stoppering qualification rate |
>=99% |
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Laminar air cleanliness |
100grade |
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Vacuum pumping speed |
10m3/h |
30m3/h |
50m3/h |
60m3/h |
60m3/h |
100m3/h |
120m3/h |
Power consumption |
5kw |
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Power supply |
380V50Hz |
4. Successful Vial Filling Production Line Case
We did a successful pharmaceutical vail filling production line in Argentina, click on the following link to learn more details: Argentina-Vial-Filling-Production-Line-Project.
We did a successful pharmaceutical vail liquid filling production line in Zimbabwe , click on the following link to learn more details: Zimbabwe-Vial-Bottle-Liquid-Filling-Line-Project
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