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Vial Liquid Filling Sealing Production Line

Marya is one of the best vial filling machine manufacturers, can provide a wide range of automatic vial filling productiom line machines for the pharmaceutical industry. Such as vial filling and capping machine 、vial stoppering machine. Capable of handling vial sizes up to 100 ml and speeds up to 36000 per hour. Our vial filling machine can meet any requirment you need.
  • vial filling line1
  • vial washing machine1
  • vial drying machine1
  • vial filling machine1
vial filling line1

vial filling line1

vial washing machine1

vial washing machine1

vial drying machine1

vial drying machine1

vial filling machine1

vial filling machine1

Product description
Parameters

Vial Compact Line for Washing, Sterilizing & Drying, Filling & Plugging, Capping

 

For the whole vial filling production line video, please click this linkVideo for Vial Filling Stoppering Line

1. Introduction

The vial liquid filling line is composed of ultrasonic vial washing machine, dryer sterilizer, vial?injectable filling?machine, vial stoppering machine and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.

 

2.Ultrasonic Bottle Vial Washing Machine   

Automatic bottle washing machine mainly uses to ampoules, vials and oral liquid bottles. The vial washing machine’s application is wide, and easy to change standard components. Ultrasonic cleaning, circulating water, WFI, compressed air jet, etc. to clean the inside and outside of the bottle many times, preventing cross-contamination. Circulation water can recycle and filter alone, save the energy and cost. This vial washing machine can be used separately or in linkage line.

 

3.Vial Bottle Sterilization&Drying Tunnel Oven

This vial sterilizing drying tunnel oven adopts integrated tunnel drying and sterilizing structure, and consist of preheating zone, high temperature sterilizing zone, cooling zone(air cooling or water cooling+online sterilization technology), conveying belt and electric controlling parts. High temperaturer zone adopts hot air circulation heating method, and the bottle is sterilized at 350 degree and heat source removed after bottle washing, with even temperature and energy saving. The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good; Optional real-time display and printing system of sterilization temperature; 

 

4.Vial Filling and Stoppering Machine

The vial filling and stoppering machine is used for filling liquid drugs in pharmaceutical factory. The nitrogen filling and fully stoppering/partially stoppering (press-stoppering) process are completed in the same machine. The vial filling stoppering machine can complete the filling, nitrogen filling, stoppering, pressure stoppering and other procedures. Where the drug contact parts are made of 316L stainless steel or GMP compliant plastic parts, preventing pollution. The filling pump adopts ceramic (peristaltic pump) for filling. Also can choose other filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump. The vial filling machine adopts frequency converter to adjust, simple operation, high degree of automation, and can be configured with automatic counting display device.

5.Vial Capping Machine

The vial capping machine is suitable for capping production after filling and stoppering of vials. And it is also suitable for the capping of antibiotic aluminum cover and aluminum plastic cover. The whole capping machine runs steadily, compression roller cover adopts single-knife or three-knife rolling cover, easy pressure adjustment. The RABS isolation system is used to ensure a clean environment for the whole capping machine and avoid drug pollution. Abnormal conditions are handled with isolation gloves, and instruments such as a glove integrity tester can be configured. This vial capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution

 

6. Performance Features
  (1)The whole aseptic vial liquid filling sealing production line meets new GMPrequirements, and the cleaning effectmeets the newPharmacopoeiastandards and requirements;
  (2)The whole injectable vial filling line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level;
  (3)Applicable specification: 1ml-100ml vial (as per user’s requirement);
  (4)Production Capacity of pharmaceutical vial filling machine: 1000-36000BPH;
  (5)Number of filling head: 1-20, to be selected according to the output;
  (6)Filling Accuracy: ≤±1% (according to drug characteristics);
  (7)Capping qualified rate: ≥99.9%;
  (8)Compact and simple structure, occupies less area;
  (9)Stable product performance, easy and reliable operation, beautiful appearance;
  (10)High degree of automation, few operators required;
  (11)Single row or double row filling;
  (12)Optional open-RABS isolation protection system and class 100 laminar flow hood protection;
  (13)Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;
  (14)This?pharma filling machine can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.;
  (15)Full-line linkage control function;
  (16)To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used;
  (17)Applicable for wide range of bottle specifications, and easy to replace mould;
  (18)The products can be customized according to customer’s actual demand.

 

Keyword:
Vial liquid filling line
vial filling machine
vial filling line
vial filling production line
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