Vial Liquid Filling Sealing Production Line
Marya is one of the best Liquid Vial Filling Machine manufacturers, can provide a wide range of automatic vial filling production line machines for the pharmaceutical industry. Such as vial filling and capping machine 、vial stoppering machine. Capable of handling vial sizes up to 100 ml and speeds up to 36000 per hour. Our vial filling machine can meet any requirement you need.
- Product Description
- Technical Features
- Technical Parameters
- Optional Systems
- Application Scenarios
- Video
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The vial liquid filling line is composed of ultrasonic vial washing machine, dryer sterilizer, vial injectable filling machine, vial stoppering machine and vial capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, depyrogenation, cooling, bottle unscrambling, (nitrogen pre-filling), filling, (nitrogen post-filling), stopper unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately, or in linkage line. The whole line is mainly used for filling of vial liquid injections and freeze-dried powder injections in pharmaceutical factories, it can also be applied to production of antibiotics, bio-pharmaceuticals, chemical pharmaceuticals, blood products etc.
Vial Bottle/Stopper/Cap Picture
Image after filling and sealing
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►The whole aseptic vial liquid filling sealing production line meets new GMPrequirements, and the cleaning effectmeets the newPharmacopoeiastandards and requirements;
►The whole injectable vial filling line can adopt straight-line layout or wall-to-wall L-shaped layout to reduce risk of cross-contamination and ensure aseptic level;
►Applicable specification: 1ml-100ml vial (as per user’s requirement);
►Production Capacity of pharmaceutical vial filling machine: 1000-36000BPH;
►Number of filling head: 1-20, to be selected according to the output;
►Filling Accuracy: ≤±1% (according to drug characteristics);
►The vial liquid filling machine adopts various filling pumps: glass pump, metal pump, peristaltic pump, ceramic pump;
►Capping qualified rate: ≥99.9%;
►Compact and simple structure, occupies less area;
►Stable product performance, easy and reliable operation, beautiful appearance;
►High degree of automation, few operators required;
►Single row or double row filling;
►The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good;
►To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used;
►Applicable for wide range of bottle specifications, and easy to replace mould;
►The products can be customized according to customer’s actual demand; -
Model
KGF4
KGF6
KGF8
KGF10
KGF12
KGF20
KGF24
Applicable specifications
2~30ml vialbottles
Filling heads
4
6
8
10
12
20
24
Production capacity
50-100bts/min
80-150bts/min
100-200bts/min
150-300bts/min
200-400bts/min
250-500bts/min
300-600bts/min
Stoppering qualification rate
>=99%
Laminar air cleanliness
100grade
Vacuum pumping speed
10m3/h
30m3/h
50m3/h
60m3/h
60m3/h
100m3/h
120m3/h
Power consumption
5kw
Power supply
380V50Hz
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► Optional real-time display and printing system of sterilization temperature;
► Optional online sterilization function for the cooling section of hot air circulation tunnel oven;
► Optional open-RABS isolation protection system and class 100 laminar flow hood protection;
► Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;► The capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution;
► This pharma filling machine can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.;
Full-line linkage control function; -
Aseptic injections: antibiotics, chemotherapeutic drugs, biological protein preparations and other aqueous needle filling and capping.
Freeze-drying preparation: linkage freeze-drying machine to realize filling → freeze-drying → plugging → capping the whole process of automation.
Oral liquid and health care products: Chinese medicine oral liquid, probiotic liquid, collagen beverages encapsulation.
Vaccine production: Vial filling of inactivated vaccines, mRNA vaccines and other biological preparations;
CRO/CDMO: small batch flexible production and process validation for clinical trial drugs.
Years rich Industry Experience
Production Bases
Successful Projects in 60 Countries
Loyal Clientele
Invited to the Embassy of the United Republic of Tanzania in Guangzhou to discuss projects
NBA (Zimbabwe National Biotechnology Authority) conducts FAT at MARYA’s Factory
NOVO NORDISK client Visit
Argentine client visits for FAT in MARYA
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Full-process Consulting Services
Whether you are preparing to build a new pharmaceutical factory, build a cleanroom that complies with local GMP regulations, or purchase pharmaceutical equipment to develop a new production line, whether it is a separate cleanroom or pharmaceutical machine project, or a one-stop solution, Marya's professional teams in the fields of pharmaceutical technical process, process equipment, decoration engineering, HVAC engineering, pipeline engineering, utility equipment, intelligent automatic control systems, project cost and other fields can provide you with full-process technical consulting services, and solve your needs one-on-one.
2D/3D Design Modeling Services
Marya project design team is composed of professional CAD and BIM engineers with more than 20 years of comprehensive industry experience and can provide you with comprehensive design services, including but not limited to process layout drawings, technical process charts, 3D models and animations, air conditioning system scheme design, construction drawing design, plant/pharmaceutical machine layout drawings, etc.
Machine Customization Services
Based on the individual needs of clients in different countries, Marya helps you clarify specific needs, match appropriate models, and customize one stop filling solutions for sterile small-volume preparations, large-volume injections, oral liquids/syrups, solid preparations, etc.
Validation Services (FAT/SAT)
Marya will appoint an engineer with rich project management experience as the person in charge, who will be fully responsible for project management and liaison work. After the equipment is manufactured, our engineers and the buyer's representatives will participate in the FAT test. After the equipment arrives at the buyer's site, it will be installed and debugged. After the equipment reaches optimal operation, the buyer will conduct SAT testing and inspection.
Key words:
Vial liquid filling line
vial filling machine
vial filling line
vial filling production line
Liquid Vial Filling Machines
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CONTACT INFO
NO211, North Fute Road, Pudong area, Shanghai, China, 200131
CONTACT
Shanghai Office: NO211, North Fute Road, Pudong area, Shanghai, China, 200131
Changsha Office: Room 23069, Block 6, Forte Star Shine World, Yuhua District, Changsha, Hunan province
Factory 1: Hunan Marya Technology Co., Ltd. Address: No. 7 Plant, SANY Industrial Park, No. 1, SANY Road, Changsha Pilot Free Trade Zone, Hunan Province, China, 410100
Factory 2: No 555, Yupan Road, Weitang Town, Xiangcheng District, Suzhou, Jiangsu Province, China
Factory 3: 15-A, Venture Capital Industrial Square, Yanghe Road, Suzhou Industrial Park
