Vial Powder Production Line
Vial Powder Compact Line for Washing, Sterilizing & Drying, Filling & Plugging, Capping
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The vial powder filling production line is composed of ultrasonic bottle washing machine, dryer sterilizer, injectable powder filling machine,?vial powder stoppering machine, and capping machine. It can complete spraying water, ultrasonic cleaning, flushing of inner and outer wall of bottle, preheating, drying and sterilization, heat source removing, cooling, bottle unscrambling, filling, plug unscrambling, stopper pressing, cap unscrambling, capping and other complex functions, realizing automatic production of the whole process. Each machine can be used separately or in linkage line, which is mainly used in production of vial sterile powder filling
2.Ultrasonic Bottle Vial Washing Machine
|Automatic bottle washing machine mainly uses to ampoules, vials and oral liquid bottles. This vial washing machine’s application is wide, and easy to change standard components. Ultrasonic cleaning, circulating water, WFI, compressed air jet, etc. to clean the inside and outside of the bottle many times, preventing cross-contamination. Circulation water can recycle and filter alone, save the energy and cost. The washing machine can be used separately or in linkage line|
3.Sterilization&Drying Tunnel Oven
|This vial bottle sterilizing drying tunnel oven adopts integrated tunnel drying and sterilizing structure, and consist of preheating zone, high temperature sterilizing zone, cooling zone(air cooling or water cooling+online sterilization technology), conveying belt and electric controlling parts. High temperaturer zone adopts hot air circulation heating method, and the bottle is sterilized at 350 degree and heat source removed after bottle washing, with even temperature and energy saving. The heat in the hot air circulation tunnel oven is evenly distributed, and the heat resources removal effect is good. Optional real-time display and printing system of sterilization temperature;
4.Vial Powder Filling Stoppering Machine
|Vial powder filling stoppering machine is suitable for sub-packaging, nitrogen filling and stoppering of sterile powder in vials of pharmaceutical companies. The vial powder filling machine adopts electric integral controlling, screw variable conveying technology completes aseptic powder dispensed filling, and can choose single head filling or multiple head filling. Various type filling heads can be designed based on different filling volume, filling accuracy of the powder filling machine is high. Multi-head screw intermittent filling, directly filling sterile raw materials into bottles, no secondary pollution. According to user needs, A level laminar flow system and glass protection cover、 environmental monitoring system can be configured, and the RABS system ensures that the filling environment is at A-level. Built-in material feeding system, the manipulator overturns the raw material barrel, which meets GMP requirements.|
5.Vial Powder Capping Machine
|The vial powder capping machine is suitable for capping production after filling and stoppering of vials. And it is also suitable for the capping of antibiotic aluminum cover and aluminum plastic cover. The whole capping machine runs steadily, compression roller cover adopts single-knife or three-knife rolling cover, easy pressure adjustment. This vial capping machine can be equipped with dust exhaust device, which can absorb aluminum scraps produced during capping and thus reduce the risk of environmental pollution. The RABS isolation system is used to ensure a clean environment for the whole machine and avoid drug pollution. Abnormal conditions are handled with isolation gloves, and instruments such as a glove integrity tester can be configured.|
6. Performance Features
(1)The whole?dry powder filling line meets new GMP?requirements, and the cleaning effect?meets the new?Pharmacopoeia?standards and requirements.
(2)The whole powder filling line can adopt straight-line layout to reduce risk of drug cross-contamination and ensure aseptic level.
(3)Applicable specification: 5ml-50ml vial (as per user’s requirement)
(4)Production Capacity: 6000-30000BPH
(5)Number of filling head: 1-4, to be selected according to output
(6)Vial Powder Filling Machine Filling Accuracy: ≤?±1% (according to drug characteristics)
(7)Capping qualified rate: ≥99.9%
(8)Compact and simple structure, occupies less area;
(9)Stable product performance, easy and reliable operation, beautiful appearance;
(10)High degree of automation, fewer operators required;
(11)The feeding system adopts various aseptic material transfer, which meets GMP requirement.
(12)Optional open-RABS isolation protection system and class 100 laminar flow hood protection;
(13)Optional high-performance no-bottle-no-filling, no bottle no stoppering, no bottle no capping and squeeze stop functions;
(14)The auger powder filling machine?can be equipped with online monitoring system to monitor key factors that affect product quality (such as dust particles, planktonic bacteria, wind speed, wind pressure, etc.).
(15)Full-line linkage control function;
(16)To realize fully automatic control and monitor of production process, high precision colored touch screen operation monitoring, PLC automatic control & automatic protection, main machine frequency conversion speed regulation and other control technology are used.
(17)Applicable for wide range of bottle specifications, and easy to replace mould.
(18)The products can be customized according to actual demand of customers.
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