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Sterile Pharmaceutical Filling Line
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Vial Filling Line
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Syringe Filling Line
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Cartridge Filling Line
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RTU Container Filling Line
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Ampoule Filling Line
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Sterile Isolator System
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Sterile Formulation System
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SVP(Small Volume Parenteral)Preparation System
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LVP(Large Volume Parenteral)Preparation System
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CIP(Cleaning In Place)Station System
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Stainless Vessel
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Sterile Water Treatment System
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Pharmaceutical Purified Water Generator
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Pharmaceutical Water Distribution System
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Pharmaceutical Water for Injection (WFI) Machine
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Pharmaceutical Pure Steam Generator
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Cleanroom System
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Other Pharmaceutical Machinery
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Solid Medicine Production Line
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IV Fluid Production Line
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Oral Liquid Production Line
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Packaging Machine
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Other Pharmaceutical Machinery
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Mini BFS Machine
BFS machine is suitable for liquid filling in pharmaceutical, chemical and food industries with aseptic or non-aseptic packaging in plastic containers.




Product Description
1. Main Applications
Plastic bottle blow fill seal machine (BFS machine) is an advanced technology that integrates molding, filling and sealing under complete control, which enables liquid to be packaged in polypropylene/high-density & low-density polyethylene plastic bottle, and the whole production process automatically completes the followings in a controlled environment (aseptic environment):
- Extrude plastic particles into plastic preform at high temperature.
- Then the preform is blown into a container by sterilized and filtered air.
- Filling liquid that have been sterilized and filtered.
- Tight sealing of containers after filling.
2. Performance Features
- The design, MOC, manufacturing, assembly and debugging of the BFS machine meet the requirements of the new GMP standards for drug production.
- The plastic bottle blow fill seal machine has advanced equipment, unique and reasonable structure, stable and reliable
performance.
- Applicable Specification: 0.2ml-1000ml plastic bottle (as per user’s requirements).
- Production Capacity: 1000-18000BPH.
- The number of bottles made each time: 1-30 bottles/mould, can be selected based on production capacity.
- Filling accuracy of bfs filling machine: ≤ ±1% (according to drug characteristics)
- The BFS machine is integrated with bottle-making, filling and sealing, with compact structure and occupies small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
- The plastic particles are plasticized by a low speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
- Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
- Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on man-machine interface.
- High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
- For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
- The filling system is accurately calculated by time pressure method with high filling precision, which can meet filling range of 0.2ml-2000ml to ensure production speed.
- Pharmaceutical bfs machine has black and white sections, the moving parts are isolated in non-clean are(black area), and only the basic components and operations are kept in clean area(white area), which reduces the area of clean room and the number of particles in clean room.
- Automatic in-place cleaning / in-place sterilization function (CIP/SIP) can be realized.
- Configurable on-line monitoring system for dust particles and plankton bacteria.
- In the process of bottle transfer, the inner surface of interface is not in contact with parts, which eliminates the produce of visible foreign matter.
- The blow fill seal equipment can realize fully automatic control and monitor of production process, high precision color touch screen operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation and other control technology are used.
- The products can be customized according to actual demand of customers.
Keyword:
Mini BFS Machine
Plastic BFS Machine
Blow Filling Sealing Machine
Plastic Mini BFS Machine
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Changsha Office: Room 23069, Block 6, Forte Star Shine World, Yuhua District, Changsha, Hunan province
Factory 1: Hunan Marya Technology Co., Ltd. Address: No. 7 Plant, SANY Industrial Park, No. 1, SANY Road, Changsha Pilot Free Trade Zone, Hunan Province, China, 410100
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