1. Classification:

1）General formulation system: It is used for general small molecule chemical preparation, such as aqueous injection, lyophilized powder injection and so on.

2）Complex formulation system: It is used in the production of preparations with complex processes, such as suspensions, emulsions, liposomes, microspheres and other special preparations.

3）Biological formulation system: It is used for the preparation of various products of biological engineering technology, such as the semi-finished preparation of antibodies, vaccines, blood products, recombinant proteins and so on, and it can also be used for the preparation of culture medium production, purified buffer solution and other auxiliary liquid.

2. Advantages:

3.Design details：
1) We can provide exquisite pharmaceutical grade stainless steel tanks ranging from 2L to 12000L, with internal material of 316L and an electrolytic polishing process Ra<0.4 μ m, which makes it have no hard-to-clean places and can meet the requirements of PED of EU and FDA certification.

2) All the connections to the tanks adopt clamps and NA, and the sealing material is EPDM or PTFE, which is in compliance with FDA. Jacket nozzle connection adopts Union or flange, and the sealing gasket is made of PTFE.

3) Each tank is equipped with a set of safety device including a burst disc or safety valve and a site pressure indicator to assure the safety of equipment and personnel to the largest extent.

4) The weighing or liquid level detecting system is used for water addition and material feeding control.

5) Before the WFI (water for injection) enters the preparation tank, we can use a clean grade sterile double tube plate heat ex-changer to cool it to the set temperature, which can also be used in integrity testing of the liquid filter element.

6) The temperature control and display of the product is realized by the temperature probe installed at the bottom of the tank, and the pressure control and display of the tank is realized by the pressure probe installed at the top of the tank.

7) To fully mix the product and speed heat transmitting, we install a magnetic stirrer driven by electromagnetic coupling with frequency conversion speed regulation at the bottom of the tank, or install a mechanical stirrer with frequency conversion at the top of the tank.

8) All the sterile tanks are equipped with spray ball to complete CIP. 

9) Sterile ventilation and air exhaust filters are installed on the top of every tank, to assure that all operations are under the sterile conditions.

10) The tanks are all equipped with sight glasses with illumination to monitor and control the level. 

11) We use a sterilization grade liquid filter which is made of polyethersulfone (PES), can withstand solutions of pH 1-14 and temperatures up to 150℃, and has good resistance to organic solvents. It has excellent filtration performance and reliable bacterial retention ability, fully meeting the filtration requirements of pharmaceutical processes.

 4.Design parameters：