The disposable aseptic filling bag includes high buffer bag, filling pipeline and filling needle. The high buffer bag is a liquid temporary storage bag in filling process, which feedback start and stop of peristaltic pump through weighing sensor on weighing, so as to continuously replenish liquid, maintain steady liquid level height and inlet pressure, and finally ensure good filling accuracy.

The filling line includes liquid inlet pipe in front of peristaltic pump , pump pipe and outlet pipe at back of the pump, in which the pump pipe especially refers to a part of hose extruded in filling pump (that is, peristaltic pump), which is an important factor to determine filling accuracy. Each filling pump usually has two rollers, each roller is composed of 4-8 rolling pulleys, each pump tube passes through a roller to form a channel, at last two hoses converge into a channel. To counteract pulse through superposition of peaks and troughs of two channels. The liquid discharge mode of filling bag is also a factor affecting unstable filling accuracy, and the commonly used ship type and octopus type can meet the requirement of uniform liquid separation. In addition, inverted trapezoidal bag design can minimize waste of liquid medicine.

         Figure 6: Diagram of Filling Pipeline